Publications
Deciphering Innate Immune Cell-Tumor Microenvironment Crosstalk at a Single-Cell Level (PDF)
Sugimura, R. and Chao, Y. (2022). Frontiers in Cell and Developmental Biology, 10:803947. doi: 10.3389/fcell.2022.803947
The Role of Innate Lymphoid Cells in Cancer Development and Immunotherapy (PDF)
Sugimura, R. and Wang, C.Y. (2022). Frontiers in Cell and Developmental Biology, 10:803563. doi: 10.3389/fcell.2022.803563
Single-Cell Approaches to Deconvolute the Development of HSCs
Xiang, Y. and Sugimura, R. (2021). Cells, 10(11), 2876.
Recent Advances and Future Prospects in Immune Checkpoint (ICI)-Based Combination Therapy for Advanced HCC
Dong, Y, Wong, J.S.L., Sugimura, R, Lam, K.-O., Li, B, Kwok, G.G.W., Leung, R, Chiu, J.W.Y., Cheung, T.T., Yau, T. (2021). Cancers. 13(8):1949.
Biomimetic Aorta-Gonad-Mesonephros on-a-Chip to Study Human Developmental Hematopoiesis
Sugimura, R.*, Ohta, R*., Mori, C., Li, A., Mano, T., Sano, E., Kosugi, K., Nakahata, T., Niwa, A., Saito, M., Torisawa, Y. (2020). Biomedical Microdevices.
* Equal contribution
Angiocrine Factors From HUVECs Amplify Erythroid Cells
Sugimura, R.*, Ohta, R*., Mori, C., Sano, E., Sugiyama, T., Nagasawa, T., Niwa, A., Torisawa, Y., Saito, M. (2019). Biorxiv (preprint).
* Equal contribution
Hemogenic Endothelium Differentiation From Human Pluripotent Stem Cells in a Feeder- and Xeno-Free Defined Condition
Ohta, R*., Sugimura, R.*, Niwa, A., Saito, M. (2019). Journal of Visualized Experiments.
* Equal contribution
Derivation of Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells
Sugimura, R. (2019). Methods in Molecular Biology. doi: 10.1007/978-1-4939-9524-0_3
The Significance and Application of Vascular Niche in the Development and Maintenance of Hematopoietic Stem Cells
Sugimura, R. (2018). International Journal of Hematology. doi: 10.1007/s12185-018- 2450-2
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells
Sugimura, R., Jha, D., Han, A., Soria-Valles, C., da Rocha, E., Lu, Y., Goettel, J., Serrao, E., Rowe, R., Malleshaiah, M., Wong, I., Sousa, P., Zhu, T., Ditadi, A., Keller, G., Engelman, A., Snapper, S., Doulatov, S., Daley, G. (2017). Nature, 545, 432-438.
Bioengineering Hematopoietic Stem Cell Niche Toward Regenerative Medicine
Sugimura R. (2015). Advanced Drug Delivery Reviews. S0169-409X(15)00235-5.
Homing and Migration Assays of Hematopoietic Stem/Progenitor Cells
He, X.C., Li, Z., Sugimura, R., Ross, J., Zhao, M., and Li, L. (2014). Methods in Molecular Biology, 1185:279-84.
Maternal-Imprinting at H19-Igf2 Locus Maintains Adult Hematopoietic Stem Cell Quiescence
Venkatraman, A., He, X.C., Thorvaldsen, J., Sugimura, R., Perry, P., Tao, F., Zhao, M., Christenson, M., Sanchez, R., Yu, J., Peng, L., Haug, J., Paulson, A., Li, H., Zhong, X., Clemens, T., Bartolomei, M., Li, L. (2013). Nature, 500, 345-349.
Stem Cell Dormancy: Maintaining a Reserved Population
Perry, J., He, X., Sugimura, R., and Li, L. (2013). Advances in Molecular Biology and Medicine, Volume 1, 119-132.
Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
Sugimura, R., He, X.C., Venkatraman, A., Arai, F., Box, A., Semerad, C., Haug, J., Peng, L., Zhong, X., Suda, T., Li, L. (2012). Cell, 150, 351-365.
Cooperation Between Both Wnt/{beta}-catenin and PTEN/PI3K/Akt Signaling Promotes Primitive Hematopoietic Stem Cell Self-Renewal and Expansion
Perry, J.M., He, X.C., Sugimura, R., Grindley, J.C., Haug, J.S., Ding, S., and Li, L. (2011). Genes & Development, 25, 1928-1942.
Bone Metastasis Targets the Endosteal Hematopoietic Stem Cell Niche (PDF)
Sugimura, R. and Li, L. (2011). IBMS BoneKEy, 8, 381-384.
Noncanonical Wnt Signaling in Vertebrate Development, Stem Cells, and Diseases
Sugimura, R., and Li, L. (2010a). Birth Defects Research, Part C, Embryo Today, 90, 243-256.
Shifting in Balance Between Osteogenesis and Adipogenesis Substantially Influences Hematopoiesis
Sugimura, R., and Li, L. (2010b). Journal of Molecular Cell Biology, 2, 61-62.